Circulating Tumor Cells

Accurate and reproducible detection down to 1 CTC per tube of blood

Monitor cancer status and progression
from a simple blood draw

Orion Spatial Proteomics

Circulating Tumor Cells (CTCs) shed from primary tumor provide a window into cancer status and progression from a simple blood draw.

Serial monitoring of CTC numbers and biomarker expression levels provides critical insight into cancer drug efficacy and pharmacodynamics.

CTCs are ultra-rare cells, often present in single digit numbers in a tube of blood. This places extreme demands on any platform required to deliver accurate and reproducible CTC detection and phenotyping results.

RareCyte products and services uniquely deliver CTC monitoring for clinical trials:

  • Accurate and reproducible detection down to 1 CTC per tube of blood
  • Assay design flexibility to measure biomarkers that inform response to therapy
  • Convenient logistics and workflow to support global trials

Orion Spatial Proteomics

“Using their liquid biopsy technology, RareCyte was able to develop a custom assay. Throughput the process, the RareCyte team was collaborative and insightful, showing true dedication to the project, resulting in the development of a fully validated assay.”

Erica Tobin

Associate Director, Oncology  |  KSQ Therapeutics, Inc.


CTC assays powered by RarePlex® technology

RarePlex assays are rigorously validated for accurate and reproducible detection and phenotyping of CTCs spanning a wide range of biomarkers and indications:

  • Prostate Cancer: AR, ARv7, PSMA, SYP, PSA, Muc1, MAO-A, Muc1
  • Breast Cancer: HER2, ER, PR
  • Immuno-oncology: PD-L1, IRF-1
  • Lung Cancer: EGFR, HER3
  • Melanoma: S-100, Melan-A, NG-2
  • EMT: Vimentin, N-cadherin
  • Proliferation: Ki-67
  • Other: Rad-51, gH2AX, CD11b, CD34, CD146


Learn more about RarePlex assays
Orion Spatial Proteomics

Get started with your CTC program



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