Orion Applications

Enable whole slide tissue analysis for Research and Clinical Applications

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High-plex imaging across an entire slide, in a single scan, enables spatial analysis through examining biomarker expression, cell classification, and subcellular localization. Such analysis paves a path for advancing studies in pathology, immuno-oncology, infectious disease, and many more areas of disease. The Orion™ Spatial Biology system continues to be utilized across a multitude of research and clinical applications worldwide. Read below to learn more.

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Explore research and clinical applications utilizing the Orion spatial biology platform

Nature Oncogene publication: Neoadjuvant botensilimab plus balstilimab response pattern investigated

Dr. Pashtoon Kasi, Weill Cornell Medicine
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Read the GI Research Foundation's article ➝

Editorial article: Quantitative microscopy for precision spatial biology: “From samples to knowledge”

Dr. Zbigniew Mikulski, La Jolla Institute for Immunology
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Webinar: Use of open-source software for quantitative analysis of multiplex images

Presented by Dr. Sara McArdle, La Jolla Institute of Immunology
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Webinar: Multimodal tissue imaging and machine learning to advance precision medicine

Dr. Peter K Sorger, Harvard Medical School
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Webinar: Spatial analysis and high-plex immunofluorescence to study human pancreata in type 1 diabetes

Dr. Estefania Quesada-Masachs, La Jolla Institute for Immunology
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Webinar: Multiplexed Tissue Imaging using the Orion Platform to Reveal the Spatial Biology of Cancer

Dr. Sandro Santagata, Brigham and Women’s Hospital
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See Orion citations on Google Scholar

See the list of RareCyte publications

Rapid tissue analysis for any sample

Tongue – Oral Squamous Cell Carcinoma

Whole-slide tissue section of an oral squamous cell carcinoma stained with a 16-plex biomarker panel and imaged with the Orion system in a single staining and imaging process.