2024 |
Liquid Biopsy |
Oncology |
Cancer |
Cancer-associated Macrophage-like Cells as a Prognostic Biomarker in Solid Tumors |
Journal of Liquid Biopsy |
Pirrello A |
2024 |
Liquid Biopsy |
Oncology |
Ovarian cancer |
Ovarian cancer-derived IL-4 promotes immunotherapy resistance |
Cell |
Mollaoglu G |
2024 |
Liquid Biopsy |
Oncology |
Breast cancer |
AKT and EZH2 inhibitors kill TNBCs by hijacking mechanisms of involution |
Nature |
Schade A |
2024 |
Tissue |
Oncology |
Melanoma |
Cell state dependent effects of Bmal1 on melanoma immunity and tumorigenicity |
Nature Communications |
Zhang X |
2024 |
Tissue |
Sarcopenia |
Muscular Aging |
Human skeletal muscle aging atlas |
Nature Aging |
Kedlian V |
2024 |
Tissue |
Oncology |
Cancer |
High-Plex Assessment of Biomarkers in Tumors |
Science Direct |
Aung T |
2024 |
Tissue |
Oncology |
Ovarian cancer |
Multi-Omics Analysis Reveals the Attenuation of the Interferon Pathway as a Driver of Chemo-Refractory Ovarian Cancer |
bioRxiv |
Afenteva D |
2024 |
Tissue |
Oncology |
Colorectal cancer |
Quality Control for Single Cell Analysis of High-plex Tissue Profiles using CyLinter |
National Library of Medicine |
Baker G |
2024 |
Liquid Biopsy |
NIPT |
NIPT |
360 A novel method for placental evaluation: Isolation of intact circulating trophoblast cells from maternal circulation |
American Journal of Obstetrics and Gynecology |
Helmicki C |
2024 |
Tissue |
Oncology |
Cancer |
Immunocto: a massive immune cell database auto-generated for histopathology |
arXiv |
Simard M |
2024 |
Tissue |
Oncology |
Cancer |
Phase II Study of Eribulin plus Pembrolizumab in Metastatic Soft-tissue Sarcomas: Clinical Outcomes and Biological Correlates |
Clinical Cancer Research |
Haddox C |
2024 |
Liquid Biopsy |
Oncology |
Cancer |
Circulating tumor cells as liquid biopsy markers in cancer patients |
Molecular Aspects of Medicine |
Smit D |
2024 |
Liquid Biopsy |
Oncology |
Cancer |
Mesothelin antigen density influences anti-mesothelin chimeric antigen receptor T cell cytotoxicity |
Cytotherapy |
Chu G |
2024 |
Liquid Biopsy |
Oncology |
Cancer |
Dissemination of Circulating Tumor Cells in Breast and Prostate Cancer: Implications for Early Detection |
Endocrinology |
Bae S |
2024 |
Liquid Biopsy |
NIPT |
NIPT |
Noninvasive single‐cell‐based prenatal genetic testing: A proof of concept clinical study |
Prenatal Diagnosis |
Bellair M |
2024 |
Liquid Biopsy |
Oncology |
Pancreatic cancer |
Detection of circulating tumor cells for the early detection of pancreatic cancer |
Cancer Research |
Yeo D |
2024 |
Liquid Biopsy |
Oncology |
Breast cancer |
Breast Cancer Circulating Tumor Cells: Current Clinical Applications and Future Prospects |
Clinical Chemistry |
Cani A |
2024 |
Tissue |
Oncology |
Breast cancer |
Qualification of a multiplexed tissue imaging assay and detection of novel patterns of HER2 heterogeneity in breast cancer |
npj Breast Cancer |
Guerriero J |
2023 |
Liquid Biopsy |
Oncology |
Colorectal cancer |
Circulating tumor cell enumeration, biomarker analyses, and kinetics in patients with colorectal cancer and other GI malignancies |
Frontiers in Oncology |
Malkawai W |
2023 |
Liquid Biopsy |
Oncology |
Colorectal cancer |
Liquid biopsy kinetics and detection of ERBB2 amplification/HER2-positivity in refractory hepatocellular carcinoma |
The Journal of Liquid Biopsy |
Gaddem AS |
2023 |
Tissue |
Oncology |
Colorectal cancer |
Neoadjuvant botensilimab plus balstilimab response pattern in locally advanced mismatch repair proficient colorectal cancer |
Nature Oncogene |
Kasi PM |
2023 |
Tissue |
Oncology |
Colorectal cancer |
High-plex immunofluorescence imaging and traditional histology of the same tissue section for discovering image-based biomarkers |
Nature Cancer |
Lin JR |
2023 |
Liquid Biopsy |
Oncology |
Breast cancer |
Metastasis from the tumor interior and necrotic core formation are regulated by breast cancer-derived angiopoietin-like 7 |
PNAS |
Yamamoto A |
2023 |
Tissue |
Oncology |
Colorectal cancer |
Multiplexed 3D atlas of state transitions and immune interaction in colorectal cancer |
Cell |
Lin JR |
2023 |
Liquid Biopsy |
Oncology |
Multiple solid tumor types |
Accurate isolation and detection of circulating tumor cells using enrichment-free multiparametric high resolution imaging |
Frontiers in Oncology |
Yeo D |
2022 |
Liquid Biopsy |
Oncology |
Multiple solid tumor types |
Liquid Biopsy Assessment of Circulating Tumor Cell PD‑L1 and IRF‑1 Expression in Patients with Advanced Solid Tumors Receiving Immune Checkpoint Inhibitor |
Targeted Oncology |
Kennedy L |
2022 |
Liquid Biopsy |
Oncology |
Lung adenocarcinoma |
Immunofluorescent and molecular characterization of effusion tumor cells reveal cancer site-of-origin and disease-driving mutations |
Cancer Cytopatholoty |
Zhu Y |
2022 |
Liquid Biopsy |
Oncology |
Breast cancer |
Circulating tumor cell detection: a prospective comparison between CellSearch and Rarecyte platforms in patients with progressive metastatic breast cancer. |
Breast Cancer Research and Treatment |
Dirix L |
2022 |
Tissue |
Oncology |
Ovarian cancer |
Single-cell tumor-immune microenvironment of BRCA1/2 mutated high-grade serous ovarian cancer |
Nature |
Lauonen IM |
2022 |
Liquid Biopsy |
Oncology |
Breast cancer |
Safety, Feasibility, and Merits of Longitudinal Molecular Testing of Multiple Metastatic Sites to Inform mTNBC Patient Treatment in the Intensive Trial of Omics in Cancer |
JCO Precision Oncology (ASCO) |
Burton KA |
2022 |
Liquid Biopsy |
Oncology |
Multiple solid tumor types |
Clinical Validation of a Circulating Tumor Cell Assay Using Density Centrifugation and Automated Immunofluorescence Microscopy |
American Journal of Clinical Pathology |
Sabath DE |
2022 |
Tissue |
Oncology |
Melanoma |
The Spatial Landscape of Progression and Immunoediting in Primary Melanoma at Single-Cell Resolution |
Cancer Discovery |
Nirmal AJ |
2022 |
Liquid Biopsy |
Oncology |
Multiple solid tumor types |
Beyond circulating tumor cell enumeration: cell-based liquid biopsy to asses protein biomarkers and cancer genomics |
Frontiers |
Kaldjian EP |
2022 |
Liquid Biopsy |
Immuno-oncology |
Prostate cancer |
Non-Invasive Profiling of Advanced Prostate Cancer via Multi-Parametric Liquid Biopsy and Radiomic Analysis |
International Journal of Molecular Sciences |
Morrison G |
2022 |
Liquid Biopsy |
Oncology |
NSCLC |
Single Circulating-Tumor-Cell-Targeted Sequencing to Identify Somatic Variants in Liquid Biopsies in Non-Small-Cell Lung Cancer Patients |
Current issues in Molecular biology |
Barbirou M |
2021 |
Tissue |
Oncology |
Multiple solid tumor types |
Advancing Spatial Biology through Highly Multiplexed Protein Imaging: The Orion™ Platform |
Journal of Precision Medicine |
Kaldjian EP |
2021 |
Liquid Biopsy |
Oncology |
Breast cancer |
Heterogeneity of Circulating Tumor Cell Neoplastic Subpopulations Outlined by Single-Cell Transcriptomics |
Cancers |
Pauken CM |
2021 |
Tissue |
Immuno-oncology |
Breast cancer |
Targeting immunosuppressive macrophages overcomes PARP inhibitor resistance in BRCA1-associated triple-negative breast cancer |
Nat Cancer |
Mehta AK |
2021 |
Tissue |
Oncology |
GI cancer |
HAND1 and BARX1 Act as Transcriptional and Anatomic Determinants of Malignancy in Gastrointestinal Stromal Tumor |
Clinical Cancer Research |
Hemming ML |
2021 |
Liquid Biopsy |
Oncology |
NSCLC |
Proficiency Testing to Assess Technical Performance for CTC-Processing and Detection Methods in CANCER-ID |
Clinical Chemistry |
Neves R |
2021 |
Tissue |
Oncology |
Synovial sarcoma |
Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma |
Nat Medicine |
Jerby-Arnon L |
2017 |
Liquid Biopsy |
Oncology |
Multiple solid tumor types |
A simple open-source method for highly multiplexed imaging of single cells in tissues and tumours |
bioRxiv |
Lin JR |
2021 |
Liquid Biopsy |
Oncology |
Breast cancer |
N-Acetyl-L-cysteine Promotes Ex Vivo Growth and Expansion of Single Circulating Tumor Cells by Mitigating Cellular Stress Responses |
Molecular Cancer Research |
Teng T |
2021 |
Tissue |
Immuno-oncology |
Melanoma |
Evolution of delayed resistance to immunotherapy in a melanoma responder |
Nat Medicine |
Liu D |
2021 |
Tissue |
Immuno-oncology |
Brain cancer |
Activity of PD-1 blockade with Nivolumab among patients with recurrent atypical/anaplastic meningioma: Phase II trial results |
Neuro Oncology |
Bi WL |
2021 |
Liquid Biopsy |
Oncology |
Multiple solid tumor types |
Identification and Characterization of Effusion Tumor Cells (ETCs) From Remnant Pleural Effusion Specimens |
Cancer Cytopathology |
Zhu Y |
2020 |
Liquid Biopsy |
Oncology |
Prostate cancer |
The combination of size-based separation and selection-free technology provides higher circulating tumor cells detection sensitivity than either method alone in patients with metastatic prostate cancer |
BJUI International |
Dong L |
2020 |
Tissue |
Infectious disease |
COVID-19 |
SARS-CoV-2 infection protects against rechallenge in rhesus macaques |
Science |
Chandrashekar A |
2020 |
Tissue |
Oncology |
Ovarian cancer |
A single-cell landscape of high-grade serous ovarian cancer |
Nature Medicine |
Izar B |
2019 |
Liquid Biopsy |
NIPT |
Cervical cancer |
A Rapid Method for Label-Free Enrichment of Rare Trophoblast Cells from Cervical Samples |
Scientific Reports |
Bailey-Hytholt CM |
2019 |
Liquid Biopsy |
Oncology |
Bladder cancer |
Circulating Tumor Cell and Circulating Tumor DNA Assays Reveal Complementary Information for Patients with Metastatic Urothelial Cancer |
European Urology Oncology |
Chalfin HJ |
2019 |
Tissue |
Immuno-oncology |
Multiple solid tumor types |
Qualifying antibodies for image-based immune profiling and multiplexed tissue imaging |
Nature Protocol |
Du Z |
2019 |
Liquid Biopsy |
Oncology |
Breast cancer |
PIC&RUN: An integrated assay for the detection and retrieval of single viable circulating tumor cells |
Scientific Reports |
Kamal M |
2019 |
Liquid Biopsy |
NIPT |
NIPT |
Validation Studies for Single Circulating Trophoblast Genetic Testing as a Form of Noninvasive Prenatal Diagnosis |
American Journal of Human Genetics |
Vossaert L |
2019 |
Liquid Biopsy |
Oncology |
Breast cancer |
Circulating tumor cell investigation in breast cancer patient-derived xenograft models by automated immunofluorescence staining, image acquisition, and single cell retrieval and analysis |
BMC Cancer |
Ramirez AB |
2018 |
Liquid Biopsy |
Oncology |
Prostate cancer |
Prostate Cancer Disseminated Tumor Cells are Rarely Detected in the Bone Marrow of Localized Patients Undergoing Radical Prostatectomy Across Multiple Rare Cell Detection Platforms |
The Journal of Urology |
Chalfin HJ |
2018 |
Liquid Biopsy |
Oncology |
Prostate cancer |
Optimization of Immunofluorescent Detection of Bone Marrow Disseminated Tumor Cells |
Biological Procedures Online |
Axelrod HD |
2018 |
Liquid Biopsy |
Oncology |
Prostate cancer |
Analogous detection of circulating tumor cells using the AccuCyte® -CyteFinder® system and ISET system in patients with locally advanced and metastatic prostate cancer |
Prostate |
van der Toom EE |
2018 |
Liquid Biopsy |
Oncology |
Bladder cancer |
Characterization of urothelial cancer circulating tumor cells with a novel selection-free method |
Urology / Genomics in Urologic Health and Disease |
Chalfin HJ |
2018 |
Tissue |
Immuno-oncology |
Multiple solid tumor types |
Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes |
eLife |
Lin JR |
2018 |
Tissue |
Immuno-oncology |
Melanoma |
A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade |
Cell |
Jerby-Arnon L |
2018 |
Liquid Biopsy |
NIPT |
NIPT |
Reliable detection of subchromosomal deletions and duplications using cell‐based noninvasive prenatal testing |
Prenatal Diagnosis |
Vossaert L |
2018 |
Liquid Biopsy |
Oncology |
Multiple solid tumor types |
The RareCyte platform for next-generation analysis of circulating tumor cells. |
Cytometry Part A |
Kaldjian EP |
2017 |
Liquid Biopsy |
Oncology |
Prostate cancer |
Nucleolin staining may aid in the identification of circulating prostate cancer cells |
Clinical Genitourinary Cancer |
Chalfin HJ |
2017 |
Tissue |
Oncology |
Melanoma |
Adaptive resistance of melanoma cells to RAF inhibition via reversible induction of a slowly dividing de-differentiated state |
Molecular Systems Biology |
Fallahi-Sichani M |
2017 |
Liquid Biopsy |
Oncology |
Breast cancer |
EMT cells increase breast cancer metastasis via paracrine GLI activation in neighbouring tumour cells |
Nature Communications |
Neelakantan D |
2017 |
Liquid Biopsy |
Oncology |
Multiple solid tumor types |
RareCyte® CTC Analysis Step 1: AccuCyte® Sample Preparation for the Comprehensive Recovery of Nucleated Cells from Whole Blood |
Circulating Tumor Cells: Methods and Protocols, Methods in Molecular Biology |
Ramirez AB |
2017 |
Liquid Biopsy |
Oncology |
Multiple solid tumor types |
RareCyte® CTC Analysis Step 2: Detection of Circulating Tumor Cells by CyteFinder® Automated Scanning and Semiautomated Image Analysis |
Circulating Tumor Cells: Methods and Protocols, Methods in Molecular Biology |
Werbin JL |
2017 |
Liquid Biopsy |
Oncology |
Multiple solid tumor types |
RareCyte® CTC Analysis Step 3: Using the CytePicker® Module for Individual Cell Retrieval and Subsequent Whole Genome Amplification of Circulating Tumor Cells for Genomic Analysis |
Circulating Tumor Cells: Methods and Protocols, Methods in Molecular Biology |
Stilwell JL |
2016 |
Liquid Biopsy |
NIPT |
NIPT |
Genome-wide copy number analysis on DNA from fetal cells isolated from the blood of pregnant women |
Prenatal Diagnosis |
Kølvraa S |
2016 |
Liquid Biopsy |
Oncology |
Breast cancer |
A Distributed Network for Intensive Longitudinal Monitoring in Metastatic Triple-Negative Breast Cancer |
J. National Comprehensive Cancer Network |
Blau CA |
2016 |
Liquid Biopsy |
NIPT |
NIPT |
Evidence for feasibility of fetal trophoblastic cell-based noninvasive prenatal testing |
Prenatal Diagnosis |
Breman AM |
2015 |
Liquid Biopsy |
Oncology |
Multiple solid tumor types |
High-recovery visual identification and single-cell retrieval of circulating tumor cells for genomic analysis using a dual-technology platform integrated with automated immunofluorescence staining |
BMC Cancer |
Campton DE |